Suh did not draw a penalty for his hit on Weeden during Sunday's 31-17 Detroit victory, but a review of the blow by league officials determined it was directed at Weeden's head.
It was the second major fine for Suh this season. He suffered a $100,000 reduction in his paycheck for a low block thrown on Minnesota center John Sullivan while an interception was being returned by teammate DeAndre Levy.
The Detroit Free Press reported Suh's career fines total has reached $209,000. He was also suspended two games during the 2011 campaign for intentionally stepping on the arm of Green Bay offensive lineman Evan Dietrich-Smith.
Suh, in his fourth NFL season, was the second player chosen overall in 2010.