The Tigers wrapped up the American League Central title, joining Boston, Oakland, Atlanta and the Los Angeles Dodgers among this season's division winners. Only the National League Central has yet to determine its champion and St. Louis needs only one more win to achieve that feat.
Scherzer (21-3), the major league leader in wins this season, gave up two hits over seven innings, but walked six while striking out 10.
The division title for the Tigers is their third in a row, a streak that has come after Detroit had gone without one for 24 years.
Kevin Correia (9-13) then shut down the Tigers through the remainder of a seven-inning performance, but he endured his third straight loss.