Michael Vick was 15-of-23 passing, connecting with Riley Cooper for a touchdown and throwing one interception. Vick picked up 53 yards on seven rushes for the Eagles, who have won two of their three pre-season games.
Nick Foles finished up at quarterback for Philadelphia, going 10-for-11 for 112 yards.
Brown gained 92 yards on 11 carries and Brent Celek caught four passes for 54 yards.
Jaguars quarterback Chad Henne was 11-of-18 passing for 106 yards and touchdown passes to Justin Blackmon and Allen Reisner.
Jordan Todman carried the ball eight times for Jacksonville, picking up 105 yards and scoring on a 63-yard run.
The Jaguars are 0-3 in the pre-season.