Higuain gave the Crew all the scoring they'd need in the 18th minute when he tallied on the rebound of a deflected shot by Bernardo Anor.
Then in the 67th minute, he doubled the advantage with a chip shot over Toronto goalkeeper Joe Bendik for his fourth goal in two games as Columbus (8-11-5) took the Trillium Cup for the fifth time in six years.
Toronto (4-12-8) mustered just two shots on target.
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