Pedro Florimon added a two-run homer in the seven-run 10th that lifted Minnesota to its sixth victory in seven games.
The outburst enabled Glen Perkins (2-0) to collect the win after blowing a save opportunity in the ninth inning. The Twins held a one-run lead in the ninth inning, but Los Angeles loaded the bases in the bottom of the ninth and tied the game 3-3 on a walk to Erick Aybar.
Ernesto Frieri (0-2) took the loss after allowing five runs in the 10th.
Ohio bar shooting arrested, charged with murder
LGBT community has 'bullied the American people': Bachmann