The Romanian, who notched her first career victory last week in Nuremberg, Germany, stayed hot by routing the Italian defending champ 6-0, 6-1 at Autotron Rosmalen in the Netherlands.
Others seeds, however, fared better Wednesday.
Meanwhile, fourth-seeded Kirsten Flipkens of Belgium overcame Dutch wild card Michaella Krajicek 7-6 (8-6), 7-6 (7-3).
Spanish qualifier Garbine Muguruza also moved on to the quarterfinals with a victory.
18-year-old elf alleges mall Santa pinched her buttocks on the job
Britney Spears on kissing Ryan Gosling, Justin Timberlake in the Mickey Mouse Club