Detroit pitching limited the Twins to three hits, all of them allowed by starter Rick Porcello (4-3).
The game was scoreless heading into the sixth, but the Tigers sent eight men to the plate in that frame while getting to Scott Diamond (4-6).
Miguel Cabrera was walked intentionally and Diamond then gave up the consecutive doubles to Fielder, Martinez and Peralta.
Porcello struck out five and did not walk a batter through seven innings. Closer Jose Valverde shut down the Twins in ninth in a non-save situation.