De La Rosa (7-3) registered his fifth victory in six starts, surrendering two runs on six hits. The left-hander issued a pair of walks and struck out five as the Rockies took two-of-three from the Dodgers.
Fowler's solo homer leading off the first inning gave the Rockies a quick lead and his two-run blast in the sixth provided the final margin of victory.
The Dodgers' Matt Magill (0-1) handed out nine walks over six innings in his first major-league loss. The rookie right-hander was lit up for seven runs (six earned) on five hits.
Skip Schumaker had two RBI for Los Angeles.
Millions of Getty images now available for free via embed tool
Boston schools pull out free condoms over wrapping complaints