Federer routed Somdev Devvarman 6-2, 6-1, 6-1 in 82 minutes. Federer was the more aggressive player, as shown by his 54 winners against 33 unforced errors.
Devvarman managed three break changes but Federer fought them all off. He won three-quarters of the points while serving and 53 percent off Devvarman's serve.
Ferrer dispatched fellow Spaniard Albert Montanes 6-2, 6-1, 6-3. Montanes was coming off a tournament win Saturday in Nice, France, but Ferrer was able to pile up eighth breaks in taking the win.
Ferrer totaled five unforced errors and faced just one break point in building the two-set lead. Three third-set breaks sealed the match.
No. 6-seeded Jo-Wilfried Tsonga, who took out Jarkko Nieminen 7-6 (8-6), 6-4, 6-3 and No. 10 Marin Cilic, who got past Nick Kyrgios 6-4, 6-2, 6-2, also moved into the third round with straight-set wins. Eighth-seeded Janko Tipsarevic topped Nicolas Mahut 6-3, 7-6 (7-4), 6-1 in a first-round match.
No seeded men's player lost Wednesday, although No. 30 Julien Benneteau was pushed for five sets by Tobias Kamke before coming away a 7-6 (11-9), 7-5, 5-7, 0-6, 6-4 second-round winner.
No. 24-seeded Marcos Baghdatis and unseeded Lukasz Kubot and Vasek Pospisil claimed first-round wins Wednesday was the opening round was finally completed.
Unseeded Viktor Troicki battled Daniel Gimeno-Traver for a five-set victory while Feliciano Lopez defeated Joao Sousa and Gael Monfils ousted Ernests Gulbis, both in four sets, in second-round matches.