Latos (5-0) racked up his 11th straight start without a loss to begin the season, controlling the Indians on one run. The right-hander allowed five hits and struck out seven while overcoming four walks.
Xavier Paul went 3-for-5 with a two-run single in the first inning that handed Cincinnati a 3-0 lead and the Reds never looked back in rolling to their seventh win in eight games.
Tribe starter Zach McAllister (4-4) was roughed up for 10 hits over 5 1/3 innings, surrendering three runs.
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