Cincinnati, clinging to a 5-4 lead in the third, scored seven times to break the contest open, capped by Bruce's RBI double.
Latos (4-0) earned the victory despite allowing seven runs (six earned) on nine hits and three walks through six innings. He struck out four.
Brewers starter Hiram Burgos (1-1) was flattened for 12 runs (10 earned) over three frames in his fourth major league start.
Jean Segura went 4-for-5 with a solo homer and three runs scored in the loss.
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