New York leads the Eastern Conference quarterfinal series 3-0 and can advance in the playoffs when they face the Celtics Sunday.
Anthony made 12-of-25 from the field and hit two of New York's seven 3-pointers, boosting New York to a 16-point halftime lead.
Raymond Felton added 15 points and 10 assists for the Knicks, who shot 50 percent from the field and forced 17 turnovers.
New York has not won a playoff series since a four-game sweep of Toronto in 2000.
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