Detroit moved into the No. 7 position in the Western Conference playoff race, but with one game left has yet to clinch a post-season berth. The Red Wings have not missed the playoffs since 1990.
The Red Wings have 54 points while both Columbus and Minnesota have 53. Both Detroit and Columbus have a game remaining while Minnesota has two left.
Detroit was facing a 2-1 deficit heading into the second period, but Franzen tied it 1:01 deep into the middle frame and Patrick Eaves put the Red Wings in front less than 3 minutes later.
Datsyuk delivered his 15th of the season with 47 seconds to go in the period and Justin Abdelkader added a goal late in the third.