Baltimore reliever Jim Johnson (1-2) got the first two outs in the 11th but J.P. Arencibia and Munenori Kawasaki each singled and Brett Lawrie was hit by a pitch to load the bases,
Izturis then took four straight pitches -- none of which was very close -- for a walk that forced in Arencibia.
Defense, which had been shaky earlier in the game, allowed Toronto a chance to bat in the 11th. With two runners on and two outs, J.J. Hardy singled to left. Manny Machado tried to score from second but Rajai Davis made a perfect throw to Arencibia, the Blue Jays' catcher, and got Machado by a step at the plate.
That left Esmil Rogers (1-1), who pitched a two-hit 10th, in position to collect the win. Casey Johnson had two strikeouts in a perfect ninth for his sixth save.
Toronto used four home runs -- a two-run shot by Arencibia in the second and solo homers by Davis, Edwin Encarnacion and Jose Bautista -- to build a 5-2 lead. The Orioles posted a three-run rally, that Machado capped with an RBI triple, to tie the score in the seventh.