George received 52 first-place votes and had 311 points in finishing ahead of New Orleans guard and Greivis Vasquez (146 points) and Milwaukee center Larry Sanders (141) in the voting.
The award is determined by a vote of writers and broadcasters who cover the NBA.
George, in his third year in the NBA, averaged 17.4 points over 79 games as the Pacers won the Central Division title. He also had career bests in rebounds (7.6 per game), assists (4.1) and steals (1.8).
He averaged 12.1 points and 5.6 rebounds a game last season.
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