Lowe (1-0) didn't allow a hit or a walk after entering the game with two out in the second inning.
Tepesch had to leave after taking a line drive off his right wrist. He was diagnosed with contusion and is expected to make his next start.
Joe Ortiz, Tanner Scheppers and Jason Frasor finished up the shutout for the Rangers, who have outscored Seattle 12-0 in taking the first two contests of a three-game series.
Mariners starter Brandon Maurer (1-3) absorbed the loss, surrendering two runs on two hits over 6 2/3 frames.
Beautician charged with giving client fatal silicone butt injection
Ohio bar shooting arrested, charged with murder