After Everth Cabrera also worked a walk to load the bases, Rodriguez relieved and issued yet another a free pass to Denorfia, forcing in Maybin with the decisive run.
Eric Stults (2-1) earned the decision with six full innings of three-run ball and also smacked a three-run homer en route to the win. The left-hander yielded nine hits and one walk while fanning four.
Huston Street picked up his second save as the Padres won the opener of a three-game series.
Carl Crawford went 3-for-5 with an RBI for the Dodgers.