Felix Doubront (1-0) struck out seven over five innings to get the victory, permitting two runs on four hits while overcoming four walks.
Tribe starter Ubaldo Jimenez (0-2), meanwhile, issued five bases-on-balls along with two hits over just 1 1/3 innings, yielding seven runs.
Mike Aviles knocked in a run for the Indians.
Ron Burgundy interviews Peyton Manning on SportsCenter
Toddler uninjured after being knocked over by Obama family dog