Venable's bases-clearing three-bagger in the eighth inning highlighted a five-run outburst that iced the win for San Diego, which had begun the season with five losses in six road games.
Nick Hundley added a solo shot in the victory.
The Dodgers' Ronald Belisario (0-1) absorbed the loss after surrendering a run in the seventh.
Uribe bashed a two-run homer for Los Angeles.
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