George Hill helped out with 14 points and seven rebounds as the Pacers followed up Monday's victory over Cleveland with a second straight triumph.
Gerald Green supplied some scoring punch off the bench, popping in 15 points to go along with eight rebounds in the victory.
Orlando got 10 points apiece from Arron Afflalo and Moe Harkless while tumbling to their 14th loss in 17 games.
Nikola Vucevic donated nine points and 11 rebounds for the Magic.
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