Italy scored four times in the first but managed just three hits the rest of the way while the Dominican Republic worked back into the game. Dominican Republic used a three-run seventh inning, in which Cano singled and scored to claim the win.
The Dominican Republic, one win from locking up a place in the WBC semifinals, advances to a game Thursday against the winner of Tuesday's game between Puerto Rico and the United States. Italy returns Wednesday for an elimination game against the Puerto Rico-United States loser.
Italy has been the surprise of the WBC and continued that with a fourth-run first inning that started with three walks, continued with a sacrifice fly and ended with a three-run Chris Colabello home run -- the only hit of the inning.
Jose Reyes hit a home run off the right-field foul pole in the third inning and Cano had his blast go off the second-deck facing in the sixth to get the Dominican Republic within 4-2.
Reyes, Erick Aybar and Cano had one-out singles that loaded the bases in the seventh off Italy reliever Pat Venditte (0-1) and Edwin Encarnacion walked to force in a run. Hanley Ramirez hit a sacrifice fly that tied the score and Nelson Cruz singled to right, driving in Cano.
Pedro Strop (1-0), the fourth Dominican Republic pitcher in the game, was given the win and Fernando Rodney earned a save.