George went 8-of-12 from the field as part of a 51 percent shooting effort by the Pacers, who have won eight out of 10.
Indiana closed the first half on a 23-14 run to take a 15-point lead and then outscored the Magic by 10 in the third period.
It was the 10th loss in 12 games for the Magic, who were led by 19 points from Arron Afflalo.
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