Durant scored 16 points, grabbed 12 rebounds and handed out 11 assists. With the Thunder strolling to the easy win, Durant was on the floor for a mere 27 minutes.
Russell Westbrook led Oklahoma City in scoring with 29 points while Serge Ibaka had 18 points and seven rebounds.
It was the Thunder's third straight win and they have now beaten consecutive opponents by 30 points for the first time in franchise history. Oklahoma City disposed of Chicago 102-72 on Sunday.
New Orleans, which lost for the fifth time in six games, was led by Ryan Anderson with 14 points.
Oklahoma City shot 55 percent from the floor and recorded the most one-sided victory in the history of the series.