Snedeker came into the final round tied for the top spot with James Hahn but pulled away to finish 19-under 267 -- a tournament record, besting the old mark of 268 set by Mark O'Meara in 1997 and tied by Phil Mickelson a decade later.
The win is likely to net Snedeker the world No. 4 ranking when the new list is released Monday.
Grabbing sole possession of second place at minus-17 was Chris Kirk, who fired a 6-under 66 Sunday.
Jason Day claimed sixth at minus-13 with a 67.