Bryant also provided eight rebounds, four assists and four steals as the Lakers stayed hot with their sixth win in seven contests.
Howard missed the game with a shoulder injury while World Peace was serving a one-game suspension, but Los Angeles went on a decisive 10-0 run in the fourth quarter to lock up the win.
The Nets got 30 points from Brook Lopez in the loss.
Notable deaths of 2014 [PHOTOS]
Michael Sam cut from the Dallas Cowboys