In a meeting of teams that have gotten off to good starts in the lockout-shortened season, the Senators halted the Canadiens' four-game winning streak. Ottawa has won five of its first seven games with one of its losses having come in overtime.
Jim O'Brien scored for Ottawa to forge a 1-1 tie after one period and the Senators then produced two power-play goals during the first half of the second stanza.
Alfredsson delivered the first one and Mika Zibanejad had the other less than 2 minutes later. It was the first goal of the season for both.
Anderson made 28 saves while Peter Budaj gave all five goals on 26 shots.
Beautician charged with giving client fatal silicone butt injection
Ohio bar shooting arrested, charged with murder