Kobe Bryant scored 14 points and added 14 assists, giving him three straight games in which he had 10 or more assists.
The Lakers, who won their third in a row, had 34 assists as a team to the Hornets' 21, and they won the rebounding battle 50-37.
New Orleans was led by Eric Gordon's 25 points. Gervis Vasquez added 15 points and 15 assists for the Hornets, who have lost three of their last four games.
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