Getzlaff's first tally came only 1:06 into the game and triggered a three goal onslaught that handed the Ducks a quick 3-0 lead. His second -- the eventual game-winner -- gave Anaheim a 5-3 advantage in the final frame.
Winnik added an assist and Saku Koivu also notched three points with a goal and two helpers as the Ducks began the lockout-shortened NHL season with their second triumph in two games.
Jonas Hiller turned aside 21-of-25 shots to earn the victory.
Miikka Kirprusoff made 19 saves in Calgary's loss.
Notable deaths of 2014 [PHOTOS]