Love originally broke the third and fourth metacarpals of his right hand while doing knuckle pushups during pre-season workouts and returned to the T-Wolves' lineup in November.
But he re-fractured the hand last week in a contest against Denver, and now needs surgery to correct the problem, the team said.
The procedure will be performed by Dr. Andy Weiland, a hand specialist at the Hospital for Special Surgery in New York.
Love has averaged 18.3 points and 14.0 rebounds through 18 games in limited action this season.
UPI horse racing weekend preview
Bo Jackson: I can't help Jameis Winston anymore