Harden fired in 28 points and added five assists for Houston, which broke a two-game losing skid.
Defino, meanwhile, returned from a two-game absence due to illness and pumped in 22 points to go along with eight helpers.
The Hawks couldn't preserve their four-game winning streak despite 21 points from Lou Williams.
Al Horford contributed a double-double of 18 points and 13 rebounds for Atlanta.
|Additional Sports News Stories|
HOLLYWOOD, May 25 (UPI) --Fox's Mike Darnell, who oversaw the creation of 'American Idol,' said he'll step down as the network's president of alternative entertainment in June.
WASHINGTON, May 24 (UPI) --The U.S. Food and Drug Administration says it's taken a close look at a mobile app that analyzes photos of urine samples and has been in contact with its maker.