J.J. Hickson contributed 16 points and 13 boards as Portland won for the seventh time in nine games before embarking a key four-game road trip.
The Blazers also got 16 points, five rebounds and four assists from LaMarcus Aldridge. Batum added eight assists and seven rebounds.
Philadelphia, meanwhile, fell to 1-3 in the midst on an eight-game road swing.
Jrue Holiday scored 29 points and had nine assists, but also turned the ball over seven times for the 76ers.