Manning -- making the Pro Bowl for the 12th time -- will guide the AFC squad and Rodgers will do the signal-calling for the NFC at the annual event, to be held Jan. 20 at Honolulu's Aloha Stadium.
Other quarterbacks selected to the Pro Bowl included Houston's Matt Schaub and Tom Brady of New England for the AFC, along with Atlanta's Matt Ryan and Washington rookie Robert Griffin III on the NFC side.
San Francisco landed the most selectees with nine, followed by Houston with eight.
The starting Pro Bowl tight ends will be New England's Rob Gronkowski and Tony Gonzalez Atlanta.
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