Bosh and backup center Josh Harrellson both were absent during Saturday's victory over the Utah Jazz but should be ready to go for the Heat's nationally televised Christmas Day matchup against Oklahoma City Thunder, the coach said after Monday's practice session.
"C.B. was back and they were able to get up and down, so they look better, should be able to go," Spoelstra told the South Florida Sun-Sentinel.
"It was nothing too unique or anything. I just felt like crap, stayed in bed for a couple of days, and I was really thinking about how exciting it would be to play at 100 percent on Christmas.
"So I kind of kept [Tuesday] in mind a lot."
Teammate Dwyane Wade said the flu bug has been hitting the Heat hard.
"Everybody on our team's been hit with the bug," he told the newspaper. "The good thing is that it didn't last too long and he was able to get back our here."