Afflalo nabbed six rebounds and Jameer Nelson supplied 16 points and six assists.
Nikola Vucevic helped out with a double-double of 13 points and 13 rebounds for Orlando.
The struggling Bobcats, meanwhile, dropped their 11th straight despite a career-high 32 points and seven assists from Kemba Walker.
Gerald Henderson put in 16 points for Charlotte.
Celebrity Breakups and divorces of 2014 [PHOTOS]