Durant finished with six assists and five rebounds while Westbrook helped out with nine assists for the Thunder, who held off a late Brooklyn comeback try and posted their sixth straight win.
Serge Ibaka (18 points) and Thabo Sefolosha (14) also reached double figures for Oklahoma City.
The Nets, meanwhile, lost at home for the first time in seven games despite a standout performance from Deron Williams, who netted a season-high 33 points along with seven assists.
Andray Blatche (19 points, 11 rebounds) and Kris Humphries (12, 12) added double-doubles in Brooklyn's loss.
Celebrity Couples of 2014 [PHOTOS]