The Rockets put up a spirited effort despite a long and emotional day in which the team first flew to Minnesota for the funeral of the daughter of Coach Kevin McHale before heading to Oklahoma City.
Alexandra McHale, 23, died Saturday after a long battle with lupus, an auto-immune disease.
Durant scored 37 points while making 13-of-22 shots. Ibaka grabbed nine rebounds in addition to scoring 23 points. Oklahoma City has won six of seven.
The game marked the return to Oklahoma City for James Harden, who was dealt by the Thunder to Houston at the start of the season. Harden made just 3-of-16 shots and scored 17 points.
Patrick Patterson had 27 to lead the Rockets, who had won three in a row.