Durant also grabbed six rebounds and four assists while sitting out most of the second half as the Thunder built a mammoth 72-29 lead in third quarter.
Oklahoma City led by as many as 55 points in the one-sided affair.
Thabo Sefolosha provided 14 points and Russell Westbrook added 12 with 11 assists for the Thunder.
Hasheem Thabeet supplied 13 points and 10 rebounds in the win.
Jeff Taylor paced the Bobcats with 10 points.