Police in San Juan said Camacho -- winner of super lightweight, lightweight and junior welterweight world titles in the 1980 -- was severely injured and a companion killed while they were sitting in a car near a shopping center in San Juan, Puerto Rico newspaper Primera Hora reported.
Authorities said one or two men got out of a sports utility vehicle, walked over to the parked car and opened fire, killing a man identified as Alberto Mojica Yamil Moreno and seriously wounding Camacho, 50.
Ernesto Torres, director of the Rio Piedras Medical Center, told newspaper the ex-boxer was shot in the neck and had lost significant amounts of blood.
Torres said an update on Camacho's prognosis would be issued Wednesday.
'How to Train Your Dragon 2' releases 5-minute clip
Yosemite climber falls 30 feet, suffers major injuries