Anthony corralled nine rebounds, J.R. Smith added 13 points with seven boards, and Raymond Felton contributed 11 points and eight assists for New York.
Rasheed Wallace finished with nine points and seven rebounds as the Knicks improved to 7-1 after sustaining their first setback Friday against Memphis.
The Pacers, meanwhile, fell for the third time in four games despite 20 points from Paul George.
David West supplied 14 points and seven rebounds for Indiana.
Celebrity Breakups and divorces of 2014 [PHOTOS]