Dr. Robert Anderson of Charlotte, N.C., will operate on Jeter's ankle Saturday, the Yankees said.
The likely future Hall-of-Famer sustained the injury Saturday while fielding a ground ball in the 12th inning of New York's loss to Detroit in Game 1 of the American League Championship Series.
The Yankees have lost twice more in the ALCS in their captain's absence, putting them on the verge of post-season elimination.
Game 4 was set for Wednesday night at Comerica Park in Detroit.
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