NFL: San Francisco 45, Buffalo 3

Oct. 7, 2012 at 8:10 PM

SAN FRANCISCO, Oct. 7 (UPI) -- Alex Smith passed for three touchdowns Sunday and the San Francisco 49ers rolled up a club-record 621 yards of offense in their 45-3 pasting of Buffalo.

Smith amassed 303 yards, going 18-of-24, while Frank Gore dominated on the ground, running for 106 yards and a score on 14 carries for the 49ers (4-1).

Michael Crabtree and Vernon Davis teamed up for 219 yards and a TD on 11 receptions for the 49ers, who have won their last two games by a combined score of 79-3.

Buffalo (2-3) got only 126 yards from quarterback Ryan Fitzpatrick, who could manage just 10 total first downs in Buffalo's second straight one-sided loss.

Related UPI Stories
Latest Headlines
Trending Stories
Report: Miami Dolphins among teams interested in New Orleans Saints' Sean Payton
Joey Logano dominates Bank of America 500
Eli Manning, Larry Donnell connect in last minute to lead Giants past 49ers
USC's Steve Sarkisian pushed into personal leave