Kenseth took the lead just after the massive pileup on the last turn of the final lap, which was triggered when then-leader Tony Stewart made contact with Michael Waltrip, spun around and ended up on top of Kasey Kahne's car.
Several Sprint Cup title contenders were involved the massive smashup, which came at the end of a two-lap shootout set up by Jamie McMurray's crash earlier in the closing laps.
No injuries were reported in the mishaps.
Kenseth's win was his second of the year following his season-opening triumph at the Daytona 500.
Swim Week Miami Beach 2014 [PHOTOS]