Scheepers picked up her first WTA championship last year with an unseeded run through the field in China. She's seeded fifth this year and opened first-round play with a 6-0, 6-3 win over wild-card entrant Wang Qiang.
Scheepers dropped just 14 points over eight service games in winning 71 percent of the points on serve. She didn't face a break point while finishing off four of her five break opportunities.
Bojana Jovanovski also advanced with a lopsided victory, stopping Timea Babos 6-1, 6-3 in a little more than an hour. Jovanovski piled up six breaks on the day.
Also Monday, Mandy Minella got by Pauline Parmentier 7-5, 3-6, 6-3 and Laura Robson advanced when Maria-Teresa Torro-Flor retired in the second set. Robson was up 6-2, 3-1 when play was stopped.
World No. 10 Marion Bartoli is the top seed for the $220,000 Guangzhou International.