Chen (10-6) didn't allow a runner to reach as far as third base in the dominating performance, limiting the Rays to five hits while issuing a single walk and striking out four.
Pedro Strop and Jim Johnson completed the whitewash as the Orioles evened their three-game series.
Jeremy Hellickson (6-7) absorbed the loss for Tampa Bay, lasting only four innings. He gave up four runs on eight hits.
2014: NFL Cheerleaders [PHOTOS]
Michael Sam cut from the Dallas Cowboys