Crisp finished 3-for-6 with three runs scored while Chris Carter added a bases-empty clout and drove in three runs for the Athletics, who clinched their three-game series and improved to 16-2 in July.
Yoenis Cespedes, Brandon Inge and Brandon Hicks each chipped in with a pair of RBI as the A's tied a franchise record for the largest margin of victory in a shutout.
A.J. Griffin (3-0) struck out nine over six shutout innings to earn the win, scattering three hits while overcoming a pair of walks.
Toronto's Rickie Romero (8-7) lasted only 1 1/3 innings. The Blue Jays left-hander walked six and was lit up for eight runs on four hits while losing his sixth straight start.
Wisconsin business offering 'therapeutic cuddling' forced to close
Video of Victoria’s Secret models trying to 'twerk' hits Instagram