The Rangers never trailed after taking a 4-0 lead in the second inning, three of the runs scoring on Murphy's first homer. Detroit, however, kept fighting back and closed within two thanks to a four-run eighth.
Murphy hit a solo shot in the fourth and drove in a run with a fifth-inning single. Ian Kinsler added a two-run homer in the fourth and Leonys Martin, playing in his sixth game this season, had a two-run triple in the fifth.
Veteran Roy Oswalt (2-0), making his second start of the year, allowed five earned runs on 13 hits over six innings but still claimed the victory.
Doug Fister (1-5) was roughed up for eight runs on nine hits in 4 1/3 innings.
Texas took two out of three in the series, during which the teams cranked out 44 runs and 70 hits.