Paszek, ranked 59th in the world, won the last three games of the match to grab a 5-6, 6-3, 7-5 victory over the fifth-seeded Kerber.
Paszek had come into the tournament at Eastbourne with a 2-10 record for the season and will find herself pitted against former No. 1 Caroline Wozniacki in next week's Wimbledon opener. Her run in Eastbourne also included wins over defending champion Marion Bartoli and 2010 Wimbledon semifinalist Tsvetana Pironkova.
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