Tomlinson -- who holds or shares 28 Chargers records -- will sign a ceremonial contract with the team and then officially retire Monday as a member of the team that drafted him with the fifth overall selection of the 2001 draft.
Tomlinson spent nine years with San Diego, including 2006, when he was named the NFL MVP with 1,815 rushing yards and 28 touchdowns. He scored 31 overall TDs that season, which stands as an NFL record.
"There have been very few players in the NFL who have meant as much to their team as LT did during his career here," Chargers head Coach Norv Turner said. "In particular, his MVP season in 2006."
Tomlinson, 32, played with the New York Jets the past two seasons after being released by the Chargers in 2010.
Over his 170 career games, Tomlinson compiled 13,684 yards and 145 touchdowns on 3,174 carries.