Stafford, whose winning bid in an auction was for $15,000, donated the tickets to the October Monday Night Football game at Soldier Field in Chicago to the University of Michigan C.S. Mott Children's Hospital, The Detroit News reported.
After winning the tickets in the auction, Stafford gave them to the family of Faith Falzone, who is having surgery this week.
Faith has a recurring infection in her colon.
"[Family members] have been through so much in the past couple years, and to see how much they all supported each other and faith through their tough times was really inspiring," Stafford said in a text message.
"I wanted to give them something they could really be excited about and something I know they deserved."
Former Michigan players Brian Griese, Steve Hutchinson and Charles Woodson support the annual UM event that included a dinner Saturday night and a golf outing featuring former Michigan players Sunday.
The event raised $1.35 million for the hospital and has brought in $5.5 million over six years.