A magnetic resonance scan showed a torn anterior cruciate ligament in the knee, the team said.
The shortstop was injured Saturday during Milwaukee's 5-2 loss to San Francisco when he slid into second base. He was carried of the field with the help of Brewers' Manager Ron Roenicke.
A 14-year veteran, Gonzalez has compiled a .259 average with four home runs, 15 RBI and eight runs scored through 24 games this season.
Former Titans kicker dies in car crash
UPI Sports Results for September 20, 2014